Goat Histone Deacetylase 2 ELISA Kit | MyBioSource MBS033341 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Goat Histone Deacetylase 2 ELISA Kit

catalog :

MBS033341

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS033341

products type :

ELISA Kit

products full name :

Goat Histone Deacetylase 2 ELISA Kit

products short name :

[Histone Deacetylase 2]

other names :

[histone deacetylase 2; Histone deacetylase 2; histone deacetylase 2; YY1-associated factor 1; transcriptional regulator homolog RPD3; histone deacetylase 2]

products gene name :

[HDAC2]

other gene names :

[HDAC2; HDAC2; HD2; RPD3; YAF1; HD2]

uniprot entry name :

HDAC2_HUMAN

reactivity :

Goat

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Sandwich

ncbi gi num :

293336691

ncbi acc num :

NP_001518.3

ncbi gb acc num :

NM_001527.3

uniprot acc num :

Q92769

ncbi mol weight :

55,364 Da

ncbi pathways :

Alcoholism Pathway (585563); Alcoholism Pathway (587116); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); Chronic Myeloid Leukemia Pathway (83116); Chronic Myeloid Leukemia Pathway (528); Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway (771595); Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway (771593); Delta-Notch Signaling Pathway (198879)

ncbi summary :

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

uniprot summary :

HDAC2: a transcriptional regulator of the histone deacetylase family, subfamily 1. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays a role in epigenetic repression and transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor; EC 3.5.1.98; Deacetylase. Chromosomal Location of Human Ortholog: 6q21. Cellular Component: nucleoplasm; heterochromatin; transcription factor complex; protein complex; Sin3 complex; ESC/E(Z) complex; nuclear chromatin; cytoplasm; replication fork; NuRD complex; nucleus. Molecular Function: deacetylase activity; nucleosomal DNA binding; protein deacetylase activity; transcription factor binding; protein binding; NAD-dependent histone deacetylase activity (H3-K9 specific); enzyme binding; NAD-dependent histone deacetylase activity (H3-K14 specific); sequence-specific DNA binding; heat shock protein binding; chromatin binding; NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity; transcription factor activity. Biological Process: establishment and/or maintenance of chromatin architecture; nerve growth factor receptor signaling pathway; positive regulation of proteolysis; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic; negative regulation of cell cycle; cardiac muscle cell development; negative regulation of gene expression, epigenetic; negative regulation of cardiac muscle cell proliferation; positive regulation of cell proliferation; dendrite development; circadian regulation of gene expression; positive regulation of oligodendrocyte differentiation; response to drug; transcription, DNA-dependent; negative regulation of transcription factor activity; hippocampus development; histone deacetylation; regulation of protein kinase B signaling cascade; response to cocaine; odontogenesis of dentine-containing teeth; chromatin remodeling; maintenance of chromatin silencing; ATP-dependent chromatin remodeling; negative regulation of MHC class II biosynthetic process; epidermal cell differentiation; positive regulation of transcription from RNA polymerase II promoter; gene expression; positive regulation of transcription factor activity; embryonic digit morphogenesis; blood coagulation; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095