catalog number :
MBS033039
products type :
ELISA Kit
products full name :
Porcine Ferroportin ELISA Kit
products short name :
[Ferroportin]
other names :
[ferroportin 1 variant I, partial; Solute carrier family 40 member 1; solute carrier family 40 member 1; iron regulated gene 1; putative ferroportin 1 variant IIIA; putative ferroportin 1 variant IIIB; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 40 (iron-regulated transporter), member 1; Ferroportin-1; Iron-regulated transporter 1]
products gene name :
[FPN]
other gene names :
[SLC40A1; SLC40A1; FPN1; HFE4; MTP1; IREG1; MST079; MSTP079; SLC11A3; FPN1; IREG1; SLC11A3]
uniprot entry name :
S40A1_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich
ncbi acc num :
AAY78556.1
ncbi mol weight :
62,542 Da
ncbi pathways :
Iron Metabolism In Placenta Pathway (672461); Iron Uptake And Transport Pathway (187191); Metal Ion SLC Transporters Pathway (161066); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (119571)
ncbi summary :
The protein encoded by this gene is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Defects in this gene are a cause of hemochromatosis type 4 (HFE4). [provided by RefSeq, Jul 2008]
uniprot summary :
SLC40A1: May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4 (HFE4). HFE4 is an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin before elevation of the transferrin saturation. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family. Chromosomal Location of Human Ortholog: 2q32. Cellular Component: multivesicular body; synaptic vesicle; integral to plasma membrane; basolateral plasma membrane; cytoplasm; plasma membrane; integral to membrane; intracellular. Molecular Function: iron ion transmembrane transporter activity; protein binding. Biological Process: anatomical structure morphogenesis; cellular iron ion homeostasis; positive regulation of transcription from RNA polymerase II promoter; lymphocyte homeostasis; transmembrane transport; negative regulation of apoptosis. Disease: Hemochromatosis, Type 4
size4 :
10x96-Strip-Wells