catalog number :
MBS032165
products type :
ELISA Kit
products full name :
Mouse Neuropeptide Y ELISA Kit
products short name :
Neuropeptide Y
other names :
neuropeptide Y, partial; Pro-neuropeptide Y; pro-neuropeptide Y; prepro-neuropeptide Y; neuropeptide Y; Neuropeptide tyrosine
products gene name :
NP-Y
other gene names :
NPY; NPY; PYY4; NPY; CPON
uniprot entry name :
NPY_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich
ncbi acc num :
AAA59945.1
ncbi mol weight :
10,851 Da
ncbi pathways :
Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); Alcoholism Pathway (585563); Alcoholism Pathway (587116); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Endothelin Pathway (672453); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Peptide Ligand-binding Receptors Pathway (106358)
ncbi summary :
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. [provided by RefSeq, Nov 2009]
uniprot summary :
NPY: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. Belongs to the NPY family. Protein type: Secreted; Hormone; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7p15.1. Cellular Component: Golgi apparatus; extracellular space; cell; extracellular region. Molecular Function: G-protein coupled receptor activity; neuropeptide hormone activity; neuropeptide Y receptor binding; calcium channel regulator activity; receptor binding. Biological Process: blood circulation; behavior; adult feeding behavior; synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; cell proliferation; neuropeptide signaling pathway; positive regulation of appetite; calcium ion transport; regulation of blood pressure; regulation of appetite; digestion; feeding behavior; cerebral cortex development; cell motility; neurite development; central nervous system neuron development