ELISA/assay

Human Insulin Like Growth Factor Binding Protein 5 ELISA Kit

MBS031035

48-Strip-Wells

435 USD

ELISA Kit

Human Insulin Like Growth Factor Binding Protein 5 ELISA Kit

Insulin Like Growth Factor Binding Protein 5

insulin-like growth factor-binding protein 5; Insulin-like growth factor-binding protein 5; insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IGF-binding protein 5; insulin-like growth factor binding protein 5

IGFBP5

IGFBP5; IGFBP5; IBP5; IBP5; IBP-5; IGF-binding protein 5; IGFBP-5

IBP5_HUMAN

Human

No significant cross-reactivity or interference between Human IGFBP5 and analogues was observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 15.6 ng/ml - 500 ng/ml. Sensitivity: 2.0 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]

Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate IGFBP5 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!

10834982

NP_000590.1

NM_000599.3

P24593

30,570 Da

Metabolism Of Proteins Pathway (106230); Myometrial Relaxation And Contraction Pathways (198759); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908); Senescence And Autophagy Pathway (198780)

IGFBP5: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Protein type: Secreted; Secreted, signal peptide; Cell cycle regulation. Chromosomal Location of Human Ortholog: 2q35. Cellular Component: insulin-like growth factor binding protein complex; extracellular space; extracellular region. Molecular Function: protein binding; insulin-like growth factor I binding; fibronectin binding; insulin-like growth factor II binding. Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; mammary gland involution; hair follicle morphogenesis; negative regulation of smooth muscle cell proliferation; negative regulation of insulin-like growth factor receptor signaling pathway; glucose metabolic process; negative regulation of smooth muscle cell migration; glucose homeostasis; signal transduction; osteoblast differentiation; positive regulation of protein kinase B signaling cascade; cellular protein metabolic process; negative regulation of translation; striated muscle cell differentiation; negative regulation of osteoblast differentiation; regulation of cell growth; skeletal muscle growth; negative regulation of cell migration

48-Strip-Wells

435 USD

96-Strip-Wells

600