ELISA/assay

Mouse Tetanus Antibody ELISA Kit

MBS030229

48-Strip-Wells

470 USD

ELISA Kit

Mouse Tetanus Antibody ELISA Kit

[Tetanus Antibody]

[Torsin-1A; Torsin-1A; torsin-1A; torsin ATPase 1; torsin ATPase-1A; dystonia 1 protein; torsin family 1 member A; dystonia 1, torsion (autosomal dominant; torsin A); torsin family 1, member A (torsin A); Dystonia 1 protein; Torsin ATPase-1A (EC:3.6.4.-); Torsin family 1 member A]

[TA]

[TOR1A; TOR1A; DQ2; DYT1; DQ2; DYT1; TA; TORA]

TOR1A_HUMAN

Mouse

332

Store all reagents at 2-8 degree C

Samples: Mouse serum, plasma or other biological fluids. Assay Type: Sandwich

Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (%) are less than 15%. [CV(%) = SD/mean ×100].

Intended Uses For the qualitative determination of Mouse Tetanus Antibody (Anti-T) in Mouse serum, plasma or other biological fluids. Principle of the Assay: The kit uses a sandwich enzyme-linked immunosorbent assay (ELISA) to analyze the existence or not of Mouse Anti-T in samples.

13878817

O14656.1

O14656

37,809 Da

Alpha-synuclein Signaling Pathway (137913)

The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1. [provided by RefSeq, Jul 2008]

TOR1A: May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. In the nucleus, displaces the nuclear membrane proteins SUN2, SYNE2 and nesprin-3/C14orf49, leaving nuclear pores and SUN1 unchanged. May form homohexamers. Interacts with TOR1AIP1 and TOR1AIP2. Interacts with KLHL14, preferentially when ATP-free. Widely expressed. Highest levels in kidney and liver. Not detected in spleen. In the brain, high levels found in the dopaminergic neurons of the substantia nigra pars compacta, as well as in the neocortex, hippocampus and cerebellum. Also high expression in the spinal cord. Belongs to the clpA/clpB family. Torsin subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 9q34. Cellular Component: synaptic vesicle; nuclear membrane; transport vesicle; growth cone; cytoskeleton; cytoplasmic vesicle membrane; intracellular membrane-bound organelle; membrane; endoplasmic reticulum lumen; nuclear envelope; cell junction; secretory granule. Molecular Function: protein binding; kinesin binding; ATPase activity; cytoskeletal protein binding; unfolded protein binding; misfolded protein binding; ATP binding. Biological Process: protein deneddylation; chaperone cofactor-dependent protein folding; organelle organization and biogenesis; regulation of dopamine uptake; synaptic vesicle transport; intermediate filament cytoskeleton organization and biogenesis; response to oxidative stress; cell adhesion; nuclear membrane organization and biogenesis; neurite development; protein homooligomerization. Disease: Dystonia 1, Torsion, Autosomal Dominant

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095