Rat Cannabinoid Receptor 1, Brain ELISA Kit | MyBioSource MBS029517 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat Cannabinoid Receptor 1, Brain ELISA Kit

catalog :

MBS029517

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS029517

products type :

ELISA Kit

products full name :

Rat Cannabinoid Receptor 1, Brain ELISA Kit

products short name :

[Cannabinoid Receptor 1, Brain]

other names :

[CNR1 protein, partial; Cannabinoid receptor 1; cannabinoid receptor 1; central cannabinoid receptor; cannabinoid receptor 1 (brain); CANN6]

products gene name :

[CNR1]

other gene names :

[CNR1; CNR1; CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5; CNR; CB-R; CB1]

uniprot entry name :

CNR1_HUMAN

reactivity :

Rat

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CNR1 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

66267480

ncbi acc num :

AAH95513.1

uniprot acc num :

P21554

ncbi mol weight :

52,858 Da

ncbi pathways :

BDNF Signaling Pathway (712093); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); N-cadherin Signaling Events Pathway (137919); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Retrograde Endocannabinoid Signaling Pathway (537443)

ncbi summary :

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]

uniprot summary :

CNR1: Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 6q14-q15. Cellular Component: growth cone; intracellular membrane-bound organelle; axon; integral to plasma membrane; plasma membrane. Molecular Function: cannabinoid receptor activity; drug binding. Biological Process: response to nicotine; negative regulation of fatty acid beta-oxidation; maternal process involved in pregnancy; regulation of synaptic transmission, glutamatergic; positive regulation of apoptosis; response to morphine; positive regulation of acute inflammatory response to antigenic stimulus; response to lipopolysaccharide; sensory perception of pain; glucose homeostasis; negative regulation of blood pressure; negative regulation of dopamine secretion; response to nutrient; aging; negative regulation of mast cell activation; negative regulation of nitric-oxide synthase activity; axonal fasciculation; negative regulation of action potential; response to cocaine; regulation of synaptic transmission, GABAergic; memory; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger; response to ethanol; positive regulation of fever; spermatogenesis; regulation of insulin secretion; positive regulation of blood pressure

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095