catalog number :
MBS028597
products type :
ELISA Kit
products full name :
Mouse alpha Smooth Muscle Actin ELISA Kit
products short name :
alpha Smooth Muscle Actin
other names :
actin, gamma-enteric smooth muscle isoform 1; Actin, gamma-enteric smooth muscle; actin, gamma-enteric smooth muscle; alpha-actin-3; actin-like protein; actin, gamma 2, smooth muscle, enteric; Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin
products gene name :
alpha-SMA
other gene names :
ACTG2; ACTG2; ACT; ACTE; VSCM; ACTA3; ACTL3; ACTSG; ACTA3; ACTL3; ACTSG
uniprot entry name :
ACTH_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of A-SMA (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001606.1
ncbi gb acc num :
NM_001615.3
ncbi mol weight :
41,877 Da
ncbi pathways :
Muscle Contraction Pathway (106261); Smooth Muscle Contraction Pathway (161025); Vascular Smooth Muscle Contraction Pathway (96530); Vascular Smooth Muscle Contraction Pathway (96866)
ncbi summary :
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]
uniprot summary :
ACTG2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Protein type: Cytoskeletal; Motility/polarity/chemotaxis; Contractile. Chromosomal Location of Human Ortholog: 2p13.1. Cellular Component: extracellular space; cytoskeleton; cytosol. Molecular Function: ATP binding. Biological Process: muscle contraction. Disease: Visceral Myopathy