catalog number :
MBS028224
products type :
ELISA Kit
products full name :
Hamster Phospholipase A2 ELISA Kit
products short name :
Phospholipase A2
other names :
phospholipase A2, membrane associated; Phospholipase A2, membrane associated; phospholipase A2, membrane associated; GIIC sPLA2; platelet phospholipase A2; group IIA phospholipase A2; eted enzyme type IIA phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A; phospholipase A2, group IIA (platelets, synovial fluid); GIIC sPLA2; Group IIA phospholipase A2; Phosphatidylcholine 2-acylhydrolase 2A
products gene name :
PL-A2
other gene names :
Pla2g2a; Pla2g2a; sPLA2
uniprot entry name :
PA2GA_RAT
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PLA2 (hereafter termed "analyte") in undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_113786.3
ncbi gb acc num :
NM_031598.3
ncbi mol weight :
16,294 Da
ncbi pathways :
Acyl Chain Remodelling Of PC Pathway (828750); Acyl Chain Remodelling Of PE Pathway (828746); Acyl Chain Remodelling Of PG Pathway (828757); Acyl Chain Remodelling Of PI Pathway (828755); Acyl Chain Remodelling Of PS Pathway (828753); Arachidonic Acid Metabolism Pathway (83383); Arachidonic Acid Metabolism Pathway (366); Eicosanoid Synthesis Pathway (198497); Ether Lipid Metabolism Pathway (83382); Ether Lipid Metabolism Pathway (365)
ncbi summary :
hydrolyzes acyl group at the sn-2 position of phospholipids, forming non-esterified fatty acids and lysophospholipids; plays a critical role in inflammation; induces proliferation of smooth muscle cells [RGD, Feb 2006]
uniprot summary :
Function: Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Catalytic activity: Phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. Cofactor: Binds 1 calcium ion per subunit . By similarity. Subcellular location: Membrane; Peripheral membrane protein. Miscellaneous: Group II phospholipase A2 is found in many cells and also extracellularly. The membrane-bound and secreted forms are identical and are encoded by a single gene. Sequence similarities: Belongs to the phospholipase A2 family.