catalog number :
MBS028050
products type :
ELISA Kit
products full name :
Hamster Eosinophil Cationic Protein ELISA Kit
products short name :
Eosinophil Cationic Protein
other names :
eosinophil cationic protein; Eosinophil cationic protein; eosinophil cationic protein; RNase 3; ribonuclease 3; cytotoxic ribonuclease; ribonuclease, RNase A family, 3; Ribonuclease 3
other gene names :
RNASE3; RNASE3; ECP; RNS3; ECP; RNS3; ECP; RNase 3
uniprot entry name :
ECP_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma, Cell Culture Supernatants, Tissue Homogenate, Urine and other Body Fluids. Detection Range: 1.56 ng/ml ~ 50 ng/ml. Sensitivity: Typically less than 0.1 ng/ml.
other info2 :
Intended Uses: This ELISA kit is intended for laboratory in vitro research use only, not for drug, household or other use! The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm by a spectrophotometer. In order to measure the concentration of Hamster ECP in the specimen, this ELISA kit includes a set of calibration standards. The calibration standards are assayed at the same time as the specimens and allow the operator to produce a standard curve of Optical Density versus Hamster ECP concentration. The concentration of Hamster ECP in the specimens is then determined by comparing the O.D. of the specimens to the standard curve.
ncbi acc num :
NP_002926.2
ncbi gb acc num :
NM_002935.2
ncbi mol weight :
18,385 Da
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532)
ncbi summary :
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]
uniprot summary :
RNASE3: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. Belongs to the pancreatic ribonuclease family. Protein type: Ribonuclease; Secreted, signal peptide; Secreted; EC 3.1.27.-. Chromosomal Location of Human Ortholog: 14q11.2. Cellular Component: extracellular space; extracellular region. Molecular Function: nucleic acid binding; endonuclease activity; ribonuclease activity. Biological Process: defense response to Gram-positive bacterium; innate immune response in mucosa; RNA catabolic process; antibacterial humoral response