catalog number :
MBS027703
products type :
ELISA Kit
products full name :
Sheep Fibroblast Growth Factor 18 ELISA Kit
products short name :
[Fibroblast Growth Factor 18]
other names :
[fibroblast growth factor 18; Fibroblast growth factor 18; fibroblast growth factor 18; fibroblast growth factor 18; zFGF5]
products gene name :
[FGF-18]
other gene names :
[FGF18; FGF18; ZFGF5; FGF-18; FGF-18]
uniprot entry name :
FGF18_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 62.5pg/ml-2000pg/ml. Sensitivity: 10pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of FGF15 (hereafter termed "analyte") in undiluted original Mouse serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_003853.1
ncbi gb acc num :
NM_003862.2
ncbi mol weight :
23,989 Da
ncbi pathways :
Activated Point Mutants Of FGFR2 Pathway (645281); Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signal Transduction Pathway (106385); Downstream Signaling Of Activated FGFR Pathway (160957); Endochondral Ossification Pathway (198812)
ncbi summary :
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008]
uniprot summary :
FGF18: Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation. Belongs to the heparin-binding growth factors family. Protein type: Cytokine; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 5q34. Cellular Component: extracellular space; nucleolus; extracellular region. Molecular Function: growth factor activity; type 2 fibroblast growth factor receptor binding; type 1 fibroblast growth factor receptor binding. Biological Process: epidermal growth factor receptor signaling pathway; nervous system development; regulation of endothelial cell proliferation; anatomical structure morphogenesis; intramembranous ossification; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; chondrocyte development; signal transduction; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of MAP kinase activity; positive regulation of chondrocyte differentiation; cell-cell signaling; positive regulation of cell proliferation; insulin receptor signaling pathway; innate immune response; angiogenesis; endochondral ossification; lung development
size4 :
10x96-Strip-Wells