catalog number :
MBS027475
products type :
ELISA Kit
products full name :
Human Interleukin 18 ELISA Kit
products short name :
Interleukin 18
other names :
interleukin-18 isoform 2 proprotein; Interleukin-18; interleukin-18; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma
products gene name :
IL18
other gene names :
IL18; IL18; IGIF; IL-18; IL-1g; IL1F4; IGIF; IL1F4; IL-18; IFN-gamma-inducing factor; IL-1 gamma
uniprot entry name :
IL18_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
ELISA Type: Sandwich
ncbi acc num :
NP_001230140.1
ncbi gb acc num :
NM_001243211.1
ncbi mol weight :
22,326 Da
ncbi pathways :
African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Cellular Roles Of Anthrax Toxin Pathway 138076!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytosolic DNA-sensing Pathway 125137!!Cytosolic DNA-sensing Pathway 124833!!IL12 Signaling Mediated By STAT4 Pathway 137936!!IL12-mediated Signaling Events Pathway 137922
ncbi summary :
The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
uniprot summary :
Function: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Subcellular location: Secreted. Post-translational modification: The pro-IL-18 precursor is processed by CASP1 or CASP4 to yield the active form. Sequence similarities: Belongs to the IL-1 family.