catalog number :
MBS026929
products type :
ELISA Kit
products full name :
Goat Connexin 40 ELISA Kit
products short name :
[Connexin 40]
other names :
[Cx40; Gap junction alpha-5 protein; gap junction alpha-5 protein; connexin-40; gap junction membrane channel protein alpha 5; gap junction protein, alpha 5; Connexin-40]
products gene name :
[CX40]
other gene names :
[Gja5; Gja5; Cx40; Cnx40; Gja-5; 5730555N10Rik; Cxn-40; Cx40]
uniprot entry name :
CXA5_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CX40 (hereafter termed "analyte") in undiluted original Goat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
CAA43850.1
ncbi mol weight :
40,413 Da
ncbi pathways :
Calcium Regulation In The Cardiac Cell Pathway (198327); Cardiac Hypertrophy: MiR-208 Pathway (198343)
uniprot summary :
GJA5: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Defects in GJA5 are a cause of familial atrial standstill (FAS). Atrial standstill is an extremely rare arrhythmia, characterized by the absence of electrical and mechanical activity in the atria. Electrocardiographically, it is characterized by bradycardia, the absence of P waves, and a junctional narrow complex escape rhythm. Defects in GJA5 are the cause of familial atrial fibrillation type 11 (ATFB11). ATFB11 is a familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. Belongs to the connexin family. Alpha-type (group II) subfamily. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Channel, misc. Cellular Component: connexon complex; cell projection; membrane; integral to plasma membrane; integral to membrane; gap junction; plasma membrane; cell junction. Molecular Function: gap junction hemi-channel activity; gap junction channel activity. Biological Process: blood vessel development; negative regulation of glomerular filtration; gap junction assembly; regulation of vasodilation; positive regulation of vasodilation; protein oligomerization; regulation of systemic arterial blood pressure; positive regulation of vasoconstriction; artery morphogenesis; regulation of systemic arterial blood pressure by renal system process; embryonic heart tube development; cell communication; negative regulation of blood pressure; skeletal development; potassium ion transport; embryonic limb morphogenesis
size4 :
10x96-Strip-Wells