catalog number :
MBS026334
products type :
ELISA Kit
products full name :
Canine Integrin ELISA Kit
products short name :
[Integrin]
other names :
[integrin; Integrin beta-1; integrin beta-1; CSAT antigen; JG22 antigen; RGD-receptor; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); CSAT antigen; JG22 antigen; RGD-receptor]
products gene name :
[ITG/CD11B]
other gene names :
[ITGB1; ITGB1]
uniprot entry name :
ITB1_CHICK
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich (Quantitative). Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ITG/CD11B (hereafter termed "analyte") in undiluted original Canine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
AAA48926.1
ncbi mol weight :
88,554 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (119314); Cell Adhesion Molecules (CAMs) Pathway (480); ECM-receptor Interaction Pathway (119313); ECM-receptor Interaction Pathway (479); Focal Adhesion Pathway (119312); Focal Adhesion Pathway (478); Integrin-mediated Cell Adhesion Pathway (199054); Phagosome Pathway (153918); Phagosome Pathway (153859); Regulation Of Actin Cytoskeleton Pathway (119319)
uniprot summary :
ITGB1: an integral membrane protein that heterodimerizes with an alpha-3 chain, forming a receptor for many extracellular-matrix proteins including fibronectin, laminin, collagen, epiligrin and thrombospondin. Beta 1 integrins recognize the amino-acid motif RGD in a wide array of ligands. Five alternatively spliced variants with alternate carboxy termini have been described. Two alternatively spliced isoforms have been described. Isoform beta-1a is widely expressed; other isoforms are generally expressed with a more restricted distribution. Isoform beta-1b is expressed in skin, liver, skeletal muscle, cardiac muscle, placenta, umbilical vein endothelial cells, neuroblastoma cells, lymphoma cells, hepatoma cells and astrocytoma cells. Isoforms beta-1c and beta-1c-2 are expressed in muscle, kidney, liver, placenta, cervical epithelium, umbilical vein endothelial cells, fibroblast cells, embryonal kidney cells, platelets and several blood cell lines. Isoform beta-c-2, rather than isoform beta-1c, is selectively expressed in primary t-cells. Isoform beta-1c is expressed in nonproliferating and differentiated prostate gland epithelial cells. Isoform beta-1d is expressed specifically in striated muscle (skeletal and cardiac muscle). Protein type: Motility/polarity/chemotaxis; Cell surface; Cell adhesion; Membrane protein, integral; Receptor, misc. Cellular Component: lamellipodium; plasma membrane; melanosome; cell junction; integrin complex. Molecular Function: protein binding; metal ion binding; receptor activity. Biological Process: integrin-mediated signaling pathway; multicellular organismal development; cell-matrix adhesion
size4 :
10x96-Strip-Wells