catalog number :
MBS026277
products type :
ELISA Kit
products full name :
Human Actinin Alpha 3 ELISA Kit
products short name :
[Actinin Alpha 3]
other names :
[alpha-actinin-3 isoform 2; Alpha-actinin-3; alpha-actinin-3; F-actin cross-linking protein; alpha-actinin skeletal muscle; actinin, alpha 3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein]
products gene name :
[ACTN3]
other gene names :
[ACTN3; ACTN3]
uniprot entry name :
ACTN3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ACTN3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001245300.1
ncbi gb acc num :
NM_001258371.1
ncbi mol weight :
103,241 Da
ncbi pathways :
Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Cell-Cell Communication Pathway (477132); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478)
ncbi summary :
This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants. The reference genome contains the non-coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Apr 2012]
uniprot summary :
ACTN3: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Belongs to the alpha-actinin family. Protein type: Cytoskeletal; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 11q13.1. Cellular Component: focal adhesion; actin filament; pseudopodium; cytosol. Molecular Function: integrin binding; protein binding; protein homodimerization activity; structural constituent of muscle; calcium ion binding; actin binding. Biological Process: regulation of apoptosis; focal adhesion formation; muscle filament sliding
size4 :
10x96-Strip-Wells