catalog number :
MBS025653
products type :
ELISA Kit
products full name :
Horse Bone Morphogenetic Protein 15 ELISA Kit
products short name :
[Bone Morphogenetic Protein 15]
other names :
[bone morphogenetic protein 15; Bone morphogenetic protein 15; bone morphogenetic protein 15; BMP-15; GDF-9B; growth/differentiation factor 9B; bone morphogenetic protein 15; Growth/differentiation factor 9B]
products gene name :
[BMP15]
other gene names :
[BMP15; BMP15; ODG2; POF4; GDF9B; GDF9B; BMP-15; GDF-9B]
uniprot entry name :
BMP15_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich (Quantitative). Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of BMP15 (hereafter termed "analyte") in undiluted original Horse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_005439.2
ncbi gb acc num :
NM_005448.2
ncbi mol weight :
45,055 Da
ncbi pathways :
Ovarian Steroidogenesis Pathway (790011); Ovarian Steroidogenesis Pathway (795173)
ncbi summary :
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.[provided by RefSeq, Sep 2009]
uniprot summary :
BMP15: May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. Defects in BMP15 are the cause of ovarian dysgenesis type 2 (ODG2); also known as X-linked hypergonadotropic ovarian dysgenesis or hypergonadotropic ovarian failure due to ovarian dysgenesis. Ovarian dysgenesis leads to ovarian failure and accounts for about half of the cases of primary amenorrhea. Defects in BMP15 are the cause of premature ovarian failure type 4 (POF4). An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. Belongs to the TGF-beta family. Protein type: Secreted, signal peptide; Cytokine; Secreted. Chromosomal Location of Human Ortholog: Xp11.2. Cellular Component: extracellular space; cytoplasm. Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding. Biological Process: BMP signaling pathway; regulation of apoptosis; ovarian follicle development; granulosa cell development; regulation of MAPKKK cascade; positive regulation of transcription, DNA-dependent; female gamete generation; cell development. Disease: Ovarian Dysgenesis 2
size4 :
10x96-Strip-Wells