catalog number :
MBS025125
products type :
ELISA Kit
products full name :
Goat Connexin 43 ELISA Kit
products short name :
[Connexin 43]
other names :
[Cx43 protein; Gap junction alpha-1 protein; gap junction alpha-1 protein; shf; sof; connexin-43; etID309742.9; short fin protein; gap junction protein, alpha 1; connexin 43; Connexin-43; Cx43; Short fin protein]
products gene name :
[CX43]
other gene names :
[cx43; gja1; gja1; cx43a1; zfCx43.3; cx43; shf; sof; Cx43]
uniprot entry name :
CXA1_DANRE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CX43 (hereafter termed "analyte") in undiluted original Goat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
AAH49297.1
ncbi mol weight :
43,455 Da
ncbi pathways :
Calcium Regulation In The Cardiac Cell Pathway (198967); EGFR1 Signaling Pathway (198963); Formation Of Annular Gap Junctions Pathway (822738); Gap Junction Pathway (119270); Gap Junction Pathway (483); Gap Junction Assembly Pathway (822732); Gap Junction Degradation Pathway (822737); Gap Junction Trafficking Pathway (822731); Gap Junction Trafficking And Regulation Pathway (822730); Membrane Trafficking Pathway (822721)
uniprot summary :
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Ref.1Plays a role in regulation of fin bone size and growth. Ref.1. Subunit structure: A connexon is composed of a hexamer of connexins. Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction gap junction. Tissue specificity: Expressed in adult ovary, heart, lens and liver. In growing caudal fins, expressed in cells flanking the germinal region of newly growing segments and in osteoblasts at segment boundaries. Ref.1 Ref.2 Ref.5. Developmental stage: Expressed both maternally and zygotically. Zygotic expression is initiated before gastrulation and persists through to day 5 of development. Levels increase in late somitogenesis, and late embryonic and early larval stages. Embryonic expression is observed in many developing tissues and organs, including the notochord and brain, and heart and vasculature. Detected throughout the lens at 24 hours post-fertilization (hpf), but by 3-4 days development, restricted to the lateral epithelium and differentiating cells in the equatorial region. Ref.2 Ref.5. Miscellaneous: Morpholino knockdown of the protein results in heart folding defects, reduced hematopoiesis and small eyes. Sequence similarities: Belongs to the connexin family. Alpha-type (group II) subfamily.
size4 :
10x96-Strip-Wells