catalog number :
MBS024977
products type :
ELISA Kit
products full name :
Human Glycated Albumin ELISA Kit
products short name :
Glycated Albumin
other names :
glutaminase liver isoform, mitochondrial isoform 4; Glutaminase liver isoform, mitochondrial; glutaminase liver isoform, mitochondrial; glutaminase I; breast cell glutaminase; L-glutamine amidohydrolase; phosphate-activated glutaminase; phosphate-dependent glutaminase; glutaminase 2 (liver, mitochondrial); L-glutaminase; L-glutamine amidohydrolase
other gene names :
GLS2; GLS2; GA; GLS; LGA; hLGA; GA; GLS
uniprot entry name :
GLSL_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.625 mg/ml - 20 mg/ml. Sensitivity: 0.1 mg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GA (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_001267726.1
ncbi gb acc num :
NM_001280797.1
ncbi mol weight :
66,323 Da
ncbi pathways :
Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Amino Acid Synthesis And Interconversion (transamination) Pathway (106173); Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); D-Glutamine And D-glutamate Metabolism Pathway (82971); D-Glutamine And D-glutamate Metabolism Pathway (340); GABAergic Synapse Pathway (377263); GABAergic Synapse Pathway (377129); Glutamate Neurotransmitter Release Cycle Pathway (106522)
ncbi summary :
The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
uniprot summary :
GLS2: Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation. Belongs to the glutaminase family. Protein type: Amino Acid Metabolism - arginine and proline; Mitochondrial; Other Amino Acids Metabolism - D-Glutamine and D-glutamate; EC 3.5.1.2; Amino Acid Metabolism - alanine, aspartate and glutamate; Hydrolase; Energy Metabolism - nitrogen. Chromosomal Location of Human Ortholog: 12q13.3. Cellular Component: mitochondrion; mitochondrial matrix. Molecular Function: protein binding; glutaminase activity. Biological Process: amino acid metabolic process; regulation of apoptosis; synaptic transmission; glutamate secretion; neurotransmitter secretion; glutamine metabolic process; amino acid biosynthetic process