Fish Glutathione Peroxidase 1 ELISA Kit | MyBioSource MBS024388 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Fish Glutathione Peroxidase 1 ELISA Kit

catalog :

MBS024388

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS024388

products type :

ELISA Kit

products full name :

Fish Glutathione Peroxidase 1 ELISA Kit

products short name :

Glutathione Peroxidase 1

other names :

glutathione peroxidase 1 isoform 1; Glutathione peroxidase 1; glutathione peroxidase 1; GPx-1; GSHPx-1; cellular glutathione peroxidase; glutathione peroxidase 1; Cellular glutathione peroxidase

products gene name :

GPX1

other gene names :

GPX1; GPX1; GPXD; GSHPX1; GPx-1; GSHPx-1

uniprot entry name :

GPX1_HUMAN

reactivity :

Fish

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GPX1 (hereafter termed this analyte) in undiluted original Fish serum, plasma and tissue homogenate samples.

ncbi gi num :

41406084

ncbi acc num :

NP_000572.2

ncbi gb acc num :

NM_000581.2

uniprot acc num :

P07203

ncbi mol weight :

22,088 Da

ncbi pathways :

Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (685553); Arachidonic Acid Metabolism Pathway (366); Direct P53 Effectors Pathway (137939); Folate Metabolism Pathway (198833); Glutathione Metabolism Pathway (82973); Glutathione Metabolism Pathway (198824); Glutathione Metabolism Pathway (343)

ncbi summary :

This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

GPX1: Protects the hemoglobin in erythrocytes from oxidative breakdown. Homotetramer. Interacts with MIEN1. Belongs to the glutathione peroxidase family. Protein type: Lipid Metabolism - arachidonic acid; Other Amino Acids Metabolism - glutathione; Oxidoreductase; EC 1.11.1.9. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: mitochondrion; mitochondrial matrix; cytoplasm; nucleus; cytosol. Molecular Function: selenium binding; glutathione binding; phospholipid-hydroperoxide glutathione peroxidase activity; glutathione peroxidase activity; SH3 domain binding. Biological Process: response to nicotine; fat cell differentiation; blood vessel endothelial cell migration; myoblast proliferation; response to toxin; skeletal muscle fiber development; negative regulation of caspase activity; thermoregulation; vasodilation; regulation of gene expression, epigenetic; endothelial cell development; response to estradiol stimulus; regulation of mammary gland epithelial cell proliferation; response to selenium ion; sensory perception of sound; glutathione metabolic process; response to symbiotic bacterium; UV protection; lipoxygenase pathway; hydrogen peroxide catabolic process; response to folic acid; regulation of neuron apoptosis; response to glucose stimulus; arachidonic acid metabolic process; response to gamma radiation; negative regulation of inflammatory response to antigenic stimulus; aging; protein amino acid oxidation; nucleobase, nucleoside and nucleotide metabolic process; skeletal muscle regeneration; angiogenesis involved in wound healing; purine base metabolic process; positive regulation of protein kinase B signaling cascade; response to xenobiotic stimulus; response to reactive oxygen species; triacylglycerol metabolic process; response to hydrogen peroxide; cell redox homeostasis; heart contraction; response to lipid hydroperoxide; purine nucleotide catabolic process; interaction with symbiont; induction of apoptosis by oxidative stress. Disease: Glutathione Peroxidase Deficiency

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage