Fish Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 ELISA Kit | MyBioSource MBS024299 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Fish Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 ELISA Kit

catalog :

MBS024299

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS024299

products type :

ELISA Kit

products full name :

Fish Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 ELISA Kit

products short name :

[Cytochrome P450, Family 19, Subfamily A, Polypeptide 1]

other names :

[cytochrome P450 19A1; Cytochrome P450 19A1; cytochrome P450 19A1; aromatase; estrogen synthase; estrogen synthetase; cytochrome P-450AROM; microsomal monooxygenase; flavoprotein-linked monooxygenase; cytochrome P450, subfamily XIX (aromatization of androgens); cytochrome P450, family 19, subfamily A, polypeptide 1; Aromatase; CYPXIX; Cytochrome P-450AROM; Estrogen synthase]

products gene name :

[CYP19A1]

other gene names :

[CYP19A1; CYP19A1; ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM; ARO1; CYAR; CYP19]

uniprot entry name :

CP19A_HUMAN

reactivity :

Fish

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/mL. Sensitivity: 0.1 ng/mL

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CYP19A1 (hereafter termed "analyte") in undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

13904860

ncbi acc num :

NP_112503.1

ncbi gb acc num :

NM_031226.2

uniprot acc num :

P11511

ncbi mol weight :

57,883 Da

ncbi pathways :

Biological Oxidations Pathway (105698); C19/C18-Steroid Hormone Biosynthesis, Pregnenolone = Androstenedione = Estrone Pathway (413383); C19/C18-Steroid Hormone Biosynthesis, Pregnenolone = Androstenedione = Estrone Pathway (468268); Cytochrome P450 - Arranged By Substrate Type Pathway (105700); Endogenous Sterols Pathway (105701); Estrogen Biosynthesis Pathway (106155); FSH Signaling Pathway (672455); Integrated Breast Cancer Pathway (219801); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976)

ncbi summary :

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]

uniprot summary :

CYP19A1: Catalyzes the formation of aromatic C18 estrogens from C19 androgens. Belongs to the cytochrome P450 family. Protein type: EC 1.14.14.14; Oxidoreductase; Lipid Metabolism - androgen and estrogen. Chromosomal Location of Human Ortholog: 15q21.1. Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum. Molecular Function: electron carrier activity; iron ion binding; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; oxygen binding. Biological Process: steroid metabolic process; xenobiotic metabolic process; androgen metabolic process; steroid biosynthetic process; sterol metabolic process; estrogen biosynthetic process. Disease: Aromatase Deficiency; Aromatase Excess Syndrome

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage