catalog number :
MBS023291
products type :
ELISA Kit
products full name :
Rat Dehydroepiandrosterone ELISA Kit
products short name :
Dehydroepiandrosterone
other names :
dehydroepiandrosterone sulfotransferase; Bile salt sulfotransferase; bile salt sulfotransferase; bile-salt sulfotranasferase 2A1; alcohol/hydroxysteroid sulfotransferase; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1; Dehydroepiandrosterone sulfotransferase; DHEA-ST; Hydroxysteroid Sulfotransferase; HST; ST2; ST2A3; Sulfotransferase 2A1
products gene name :
DHEA
other gene names :
SULT2A1; SULT2A1; HST; ST2; STD; hSTa; DHEAS; ST2A1; ST2A3; DHEA-ST; HST; STD; DHEA-ST; HST; ST2A1
uniprot entry name :
ST2A1_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
ELISA Type: Sandwich
ncbi acc num :
AAA17750.1
ncbi mol weight :
33,780 Da
ncbi pathways :
Bile Secretion Pathway 193146!!Bile Secretion Pathway 193095!!Biological Oxidations Pathway 105698!!Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Corticotropin-releasing Hormone Pathway 920957!!Cytosolic Sulfonation Of Small Molecules Pathway 105724!!Drug Induction Of Bile Acid Pathway 698755!!E2F Transcription Factor Network Pathway 137934!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977
ncbi summary :
This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. [provided by RefSeq, Mar 2010]
uniprot summary :
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Catalytic activity: 3'-phosphoadenylyl sulfate + glycolithocholate = adenosine 3',5'-bisphosphate + glycolithocholate 3-sulfate.3'-phosphoadenylyl sulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate. Subunit structure: Homodimer. Subcellular location: Cytoplasm. Tissue specificity: Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney. Post-translational modification: The N-terminus is blocked. Miscellaneous: Estrogens present in maternal circulation is predominantly derived from fetal dehydroepiandosterone sulfate which is hydrolyzed and metabolized to estrogens in placenta. Sequence similarities: Belongs to the sulfotransferase 1 family.