catalog number :
MBS023149
products type :
ELISA Kit
products full name :
Hamster Thrombin Activatable Fibrinolysis Inhibitor ELISA Kit
products short name :
Thrombin Activatable Fibrinolysis Inhibitor
other names :
thrombin-activatable fibrinolysis inhibitor; Carboxypeptidase B2; carboxypeptidase B2; carboxypeptidase R; carboxypeptidase U; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor; carboxypeptidase B2 (plasma); Carboxypeptidase R; CPR; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor
products gene name :
TAFI
other gene names :
Cpb2; Cpb2; CPR; Cpu; TAFI; AI255929; 1110032P04Rik; 4930405E17Rik; Tafi; CPR; CPU; TAFI
uniprot entry name :
CBPB2_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 3.12 ug/ml - 100 ug/ml. Sensitivity: 1.0 ug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TAFI (hereafter termed this analyte) in Hamster serum, plasma and tissue homogenate samples.
ncbi acc num :
AAF62385.1
ncbi mol weight :
48,871 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway (198335); Complement And Coagulation Cascades Pathway (83270); Complement And Coagulation Cascades Pathway (484); Pancreatic Secretion Pathway (169307); Pancreatic Secretion Pathway (169295); Protein Digestion And Absorption Pathway (172853); Protein Digestion And Absorption Pathway (171868)
uniprot summary :
CPB2: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. Belongs to the peptidase M14 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.17.20; Secreted; Secreted, signal peptide; Protease. Cellular Component: extracellular space; extracellular region. Molecular Function: peptidase activity; zinc ion binding; metallopeptidase activity; hydrolase activity; carboxypeptidase activity; metal ion binding; metallocarboxypeptidase activity. Biological Process: fibrinolysis; negative regulation of fibrinolysis; response to heat; hemostasis; blood coagulation; proteolysis