Hamster Lipoprotein Lipase ELISA Kit | MyBioSource MBS022675 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Hamster Lipoprotein Lipase ELISA Kit

catalog :

MBS022675

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS022675

products type :

ELISA Kit

products full name :

Hamster Lipoprotein Lipase ELISA Kit

products short name :

Lipoprotein Lipase

other names :

lipoprotein lipase; Lipoprotein lipase; lipoprotein lipase; lipoprotein lipase

products gene name :

LPL

other gene names :

LPL; LPL; LIPD; HDLCQ11; LIPD; LPL

uniprot entry name :

LIPL_HUMAN

reactivity :

Hamster

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 50 U/L - 1600 U/L. Sensitivity: 10 U/L.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LPL (hereafter termed "analyte") in undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

4557727

ncbi acc num :

NP_000228.1

ncbi gb acc num :

NM_000237.2

uniprot acc num :

P06858

ncbi mol weight :

53,162 Da

ncbi pathways :

Adipogenesis Pathway (198832); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Chylomicron-mediated Lipid Transport Pathway (106157); Developmental Biology Pathway (477129); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Fatty Acid Beta Oxidation Pathway (198865); Glycerolipid Metabolism Pathway (82986)

ncbi summary :

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]

uniprot summary :

LPL: The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium. Defects in LPL are the cause of lipoprotein lipase deficiency (LPL deficiency); also known as familial chylomicronemia or hyperlipoproteinemia type I. LPL deficiency chylomicronemia is a recessive disorder usually manifesting in childhood. On a normal diet, patients often present with abdominal pain, hepatosplenomegaly, lipemia retinalis, eruptive xanthomata, and massive hypertriglyceridemia, sometimes complicated with acute pancreatitis. Belongs to the AB hydrolase superfamily. Lipase family. Protein type: Phospholipase; Lipid Metabolism - glycerolipid; EC 3.1.1.34; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 8p22. Cellular Component: extracellular matrix; extracellular space; chylomicron; cell surface; plasma membrane; extracellular region. Molecular Function: heparin binding; triacylglycerol lipase activity; protein binding; lipoprotein lipase activity; apolipoprotein binding; phospholipase activity; receptor binding; triglyceride binding. Biological Process: response to drug; phototransduction, visible light; triacylglycerol metabolic process; phospholipid metabolic process; triacylglycerol catabolic process; lipoprotein metabolic process; triacylglycerol biosynthetic process; response to cold; retinoid metabolic process; fatty acid biosynthetic process. Disease: Hyperlipoproteinemia, Type I; Hyperlipidemia, Familial Combined

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage