product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Nuclear Antibody ELISA Kit
catalog :
MBS021985
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
product information
catalog number :
MBS021985
products type :
ELISA Kit
products full name :
Mouse Nuclear Antibody ELISA Kit
products short name :
Nuclear Antibody
other names :
nuclear mitotic apparatus protein 1 isoform 1; Nuclear mitotic apparatus protein 1; nuclear mitotic apparatus protein 1; SP-H antigen; structural nuclear protein; centrophilin stabilizes mitotic spindle in mitotic cells; nuclear mitotic apparatus protein 1; SP-H antigen
products gene name :
ANA
other gene names :
NUMA1; NUMA1; NUMA; NUMA; NuMA protein
uniprot entry name :
NUMA1_HUMAN
reactivity :
Mouse
sequence length :
2115
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse serum, plasma or other biological fluids. Assay Type: Qualitative Sandwich
other info2 :
Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (%) are less than 15%.
products description :
Intended Uses: The kit uses a sandwich enzyme-linked immunosorbent assay (ELISA) to qualitative analyze the existence or not of Mouse Nuclear Antibody (ANA) in Mouse serum, plasma or other biological fluids. Principle of the Assay: The kit uses a sandwich enzyme-linked immunosorbent assay (ELISA) to qualitative analyze the existence or not of Mouse Nuclear Antibody (ANA) in Mouse serum, plasma or other biological fluids.
ncbi gi num :
71361682
ncbi acc num :
NP_006176.2
ncbi gb acc num :
NM_006185.3
uniprot acc num :
Q14980
ncbi mol weight :
238,260 Da
ncbi pathways :
Caspase Cascade In Apoptosis Pathway (137974); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Centrosome Maturation Pathway (105807); G2/M Transition Pathway (105801); Mitotic G2-G2/M Phases Pathway (160942); Recruitment Of NuMA To Mitotic Centrosomes Pathway (105809); Recruitment Of Mitotic Centrosome Proteins And Complexes Pathway (105808)
ncbi summary :
This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
uniprot summary :
NuMA-1: a coiled-coil nuclear protein that is required to establish and maintain mammalian spindle poles. Dissociates from condensing chromosomes during early prophase, before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident. Two human splice-variant isoforms have been described. Protein type: Motility/polarity/chemotaxis; Cell cycle regulation. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: nucleoplasm; Golgi membrane; spindle pole; nuclear matrix; cell soma; apical part of cell; spindle microtubule; dendrite; cytoplasm; spindle; chromosome; cytosol; nucleus. Molecular Function: protein binding; microtubule binding; structural molecule activity. Biological Process: mitosis; meiotic cell cycle; establishment of mitotic spindle orientation; cell division; mitotic cell cycle; G2/M transition of mitotic cell cycle; nuclear organization and biogenesis. Disease: Acute Promyelocytic Leukemia
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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