Hamster Tumor Necrosis Factor beta ELISA Kit | MyBioSource MBS021675 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Hamster Tumor Necrosis Factor beta ELISA Kit

catalog :

MBS021675

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS021675

products type :

ELISA Kit

products full name :

Hamster Tumor Necrosis Factor beta ELISA Kit

products short name :

[Tumor Necrosis Factor beta]

products name syn :

[Lymphotoxin-alpha]

other names :

[tumor necrosis factor-beta; Lymphotoxin-alpha; lymphotoxin-alpha; LT-alpha; TNF-beta; TNF superfamily, member 1; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1; lymphotoxin alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1]

products gene name :

[TNFbeta]

other gene names :

[LTA; LTA; LT; TNFB; TNFSF1; TNFB; TNFSF1; LT-alpha]

uniprot entry name :

TNFB_HUMAN

reactivity :

Hamster

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 15.6 pg/ml - 500 pg/ml. Sensitivity: 2.0 pg/ml. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TNFB (hereafter termed this analyte) in undiluted original Hamster serum, plasma and tissue homogenate samples.

ncbi gi num :

339743

ncbi acc num :

AAB59455.1

uniprot acc num :

P01374

ncbi mol weight :

22,297 Da

ncbi pathways :

Apoptosis Pathway (198797); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); IL2 Signaling Events Mediated By STAT5 Pathway (137988); IL4-mediated Signaling Events Pathway (137933); NF-kappa B Signaling Pathway (634527)

ncbi summary :

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]

uniprot summary :

LTA: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. Genetic variations in LTA are a cause of susceptibility psoriatic arthritis (PSORAS). PSORAS is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoidlike pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis). Belongs to the tumor necrosis factor family. Protein type: Secreted; Apoptosis; Secreted, signal peptide; Cytokine. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: extracellular space; membrane. Molecular Function: cytokine activity; tumor necrosis factor receptor binding; receptor binding. Biological Process: response to drug; positive regulation of humoral immune response mediated by circulating immunoglobulin; apoptosis; positive regulation of apoptosis; response to lipopolysaccharide; signal transduction; lymph node development; humoral immune response; defense response to Gram-positive bacterium; positive regulation of interferon-gamma production; cell-cell signaling; negative regulation of fibroblast proliferation; response to hypoxia; positive regulation of chronic inflammatory response to antigenic stimulus; response to nutrient. Disease: Psoriatic Arthritis, Susceptibility To; Myocardial Infarction, Susceptibility To; Leprosy, Susceptibility To, 4

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095