catalog number :
MBS020797
products type :
ELISA Kit
products full name :
Rabbit Lipoprotein A ELISA Kit
products short name :
[Lipoprotein A]
other names :
[lipoprotein, Lp(a); Apolipoprotein(a); apolipoprotein(a); apolipoprotein(a); lp(a); apo(a); antiangiogenic AK38 protein; lipoprotein, Lp(a)]
products gene name :
[LP-A]
other gene names :
[LPA; LPA; LP; AK38; APOA; Apo(a); Lp(a)]
uniprot entry name :
APOA_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Rabbit body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 15.6 ug/ml - 500 ug/ml. Sensitivity: 2.0 ug/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LPA (hereafter termed "analyte") in undiluted original Rabbit body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
EAW47596.1
ncbi mol weight :
501,319 Da
ncbi pathways :
LDL-mediated Lipid Transport Pathway (106159); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Amb2 Integrin Signaling Pathway (137945)
ncbi summary :
The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009]
uniprot summary :
LPA: Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330. Belongs to the peptidase S1 family. Plasminogen subfamily. Protein type: EC 3.4.21.-; Inhibitor; Protease. Chromosomal Location of Human Ortholog: 6q26. Cellular Component: extracellular region. Molecular Function: heparin binding; protein binding; serine-type endopeptidase activity; fibronectin binding; endopeptidase inhibitor activity; apolipoprotein binding. Biological Process: receptor-mediated endocytosis; blood circulation; lipoprotein metabolic process; lipid metabolic process; proteolysis; lipid transport
size4 :
10x96-Strip-Wells