catalog number :
MBS020667
products type :
ELISA Kit
products full name :
Porcine Major Histocompatibility Complex III ELISA Kit
products short name :
[Major Histocompatibility Complex III]
other names :
[MutSH5; MutS protein homolog 5; mutS protein homolog 5; mutS homolog 5]
products gene name :
[MHC 3]
other gene names :
[MSH5; MSH5; G7; NG23; MUTSH5; hMSH5]
uniprot entry name :
MSH5_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MHCIII (hereafter termed this analyte) in undiluted original Porcine serum, plasma and tissue homogenate samples.
ncbi acc num :
AAD21822.1
ncbi mol weight :
92,875 Da
ncbi pathways :
Cell Cycle Pathway (530733); Meiosis Pathway (477133); Meiotic Recombination Pathway (205242); Ovarian Infertility Genes Pathway (198801)
ncbi summary :
This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011]
uniprot summary :
MSH5: Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis. Belongs to the DNA mismatch repair MutS family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: synaptonemal complex. Molecular Function: DNA-dependent ATPase activity; protein binding; damaged DNA binding; ATP binding; mismatched DNA binding. Biological Process: homologous chromosome segregation; meiotic recombination; chiasma formation; meiotic mismatch repair
size4 :
10x96-Strip-Wells