product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Fatty Acid Synthase ELISA Kit
catalog :
MBS020522
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS020522
products type :
ELISA Kit
products full name :
Mouse Fatty Acid Synthase ELISA Kit
products short name :
Fatty Acid Synthase
other names :
fatty acid synthase; Fatty acid synthase; fatty acid synthase; short chain dehydrogenase/reductase family 27X, member 1; fatty acid synthase
products gene name :
FAS
other gene names :
FASN; FASN; FAS; OA-519; SDR27X1; FAS
uniprot entry name :
FAS_HUMAN
reactivity :
Mouse
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 3.12 U/L - 100 U/L. Sensitivity: 1.0 U/L.
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FAS (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.
ncbi gi num :
41872631
ncbi acc num :
NP_004095.4
ncbi gb acc num :
NM_004104.4
uniprot acc num :
P49327
ncbi mol weight :
273,427 Da
ncbi pathways :
AMPK Signaling Pathway (198868); Activation Of Gene Expression By SREBP (SREBF) Pathway (685552); ChREBP Activates Metabolic Gene Expression Pathway (106104); Fatty Acid Biosynthesis Pathway (198873); Fatty Acyl-CoA Biosynthesis Pathway (106115); Fatty Acid Biosynthesis Pathway (82933); Fatty Acid Biosynthesis Pathway (294); Fatty Acid Biosynthesis, Elongation Pathway (413379); Fatty Acid Biosynthesis, Elongation Pathway (468276); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977)
ncbi summary :
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
uniprot summary :
FASN: a multifunctional enzyme. Catalyzes the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. Protein type: EC 2.3.1.85; EC 4.2.1.59; Acetyltransferase; EC 2.3.1.38; EC 3.1.2.14; EC 2.3.1.41; Lyase; EC 1.1.1.100; Lipid Metabolism - fatty acid biosynthesis; EC 1.3.1.39; Oxidoreductase; EC 2.3.1.39; Hydrolase. Chromosomal Location of Human Ortholog: 17q25. Cellular Component: Golgi apparatus; membrane; mitochondrion; glycogen granule; cytoplasm; melanosome; plasma membrane; cytosol. Molecular Function: protein homodimerization activity; fatty-acid synthase activity; myristoyl-[acyl-carrier-protein] hydrolase activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; zinc ion binding; enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; drug binding; [acyl-carrier-protein] S-acetyltransferase activity; 3-oxoacyl-[acyl-carrier-protein] reductase activity; protein binding; 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; oleoyl-[acyl-carrier-protein] hydrolase activity; [acyl-carrier-protein] S-malonyltransferase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity. Biological Process: osteoblast differentiation; vitamin metabolic process; acetyl-CoA metabolic process; pantothenate metabolic process; positive regulation of cellular metabolic process; energy reserve metabolic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; fatty acid metabolic process; fatty acid biosynthetic process; water-soluble vitamin metabolic process
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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