ELISA/assay

Human Transferrin ELISA Kit

MBS020515

96 Strip Wells

600 USD

ELISA Kit

Human Transferrin ELISA Kit

Transferrin

transferrin; Serotransferrin; serotransferrin; siderophilin; beta-1 metal-binding globulin; transferrin; Beta-1 metal-binding globulin; Siderophilin

TF

TF; TF; TFQTL1; PRO1557; PRO2086; Transferrin

TRFE_HUMAN

Human

Store all reagents at 2-8 degree C

ELISA Type: Sandwich

339453

AAA61140.1

P02787

77,064 Da

EPHB Forward Signaling Pathway 138047!!HIF-1 Signaling Pathway 695200!!HIF-1-alpha Transcription Factor Network Pathway 138045!!Hemostasis Pathway 106028!!Iron Metabolism In Placenta Pathway 672461!!Iron Uptake And Transport Pathway 187191!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220!!Platelet Activation, Signaling And Aggregation Pathway 106034!!Platelet Degranulation Pathway 106050

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]

Function: Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Subunit structure: Monomer. Subcellular location: Secreted. Tissue specificity: Expressed by the liver and secreted in plasma. Polymorphism: Different polymorphic variants of transferrin are known. The sequence shown is the predominant electrophoretic variant (C1 or TF*C1). Involvement in disease: Atransferrinemia (ATRAF) [MIM:209300]: A rare autosomal recessive disorder characterized by abnormal synthesis of transferrin leading to iron overload and microcytic hypochromic anemia.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.4 Ref.37. Sequence similarities: Belongs to the transferrin family.Contains 2 transferrin-like domains. Sequence caution: The sequence AAF22007.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

96 Strip Wells

600 USD