Mouse Glucagon Like Peptide 2 ELISA Kit | MyBioSource MBS019927 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Glucagon Like Peptide 2 ELISA Kit

catalog :

MBS019927

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS019927

products type :

ELISA Kit

products full name :

Mouse Glucagon Like Peptide 2 ELISA Kit

products short name :

Glucagon Like Peptide 2

other names :

glucagon preproprotein; Glucagon; glucagon; preproglucagon; glucagon-like peptide 1; glucagon-like peptide 2; glicentin-related polypeptide; glucagon; Incretin hormone

products gene name :

GLP-2

other gene names :

GCG; GCG; GLP1; GLP2; GRPP; GRPP; OXM; OXY; GLP-1; GLP-1(7-37); GLP-1(7-36); GLP-2

uniprot entry name :

GLUC_HUMAN

reactivity :

Mouse

sequence length :

180

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Culture Supernatants, Body Fluid And Tissue Homogenate. Detection Range: 0 ~ 8.0 ng/ml. Sensitivity: Typically less than 0.1 ng/ml.

other info2 :

Intended Uses: This ELISA kit is intended for laboratory in vitro research use only, not for drug, household or other use! The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm by a spectrophotometer. In order to measure the concentration of Mouse GLP-2 in the sample, this ELISA kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus Mouse GLP-2 concentration. The concentration of Mouse GLP-2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

4503945

ncbi acc num :

NP_002045.1

ncbi gb acc num :

NM_002054.4

uniprot acc num :

P01275

ncbi mol weight :

20,909 Da

ncbi pathways :

Class B/2 (Secretin Family Receptors) Pathway (106378); FOXA1 Transcription Factor Network Pathway (137979); G Alpha (q) Signalling Events Pathway (106043); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Glucagon Signaling In Metabolic Regulation Pathway (106097); Glucagon-like Peptide-1 (GLP1) Regulates Insulin Secretion Pathway (105925); Glucagon-type Ligand Receptors Pathway (106380)

ncbi summary :

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]

uniprot summary :

GCG: Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. GLP-1 and GLP-2 are induced in response to nutrient ingestion. Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain. Belongs to the glucagon family. Protein type: Hormone; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 2q36-q37. Cellular Component: extracellular space; endoplasmic reticulum lumen; extracellular region; plasma membrane. Molecular Function: identical protein binding; protein binding; hormone activity; glucagon receptor binding; receptor binding. Biological Process: positive regulation of protein binding; positive regulation of histone H3-K4 methylation; signal transduction; positive regulation of peptidyl-serine phosphorylation; G-protein signaling, coupled to cAMP nucleotide second messenger; response to starvation; cell proliferation; G-protein coupled receptor protein signaling pathway; cellular protein metabolic process; positive regulation of protein kinase activity; positive regulation of cAMP biosynthetic process; energy reserve metabolic process; feeding behavior; regulation of insulin secretion; negative regulation of apoptosis

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage