catalog number :
MBS019752
products type :
ELISA Kit
products full name :
Human Acyl Ghrelin ELISA Kit
products short name :
[Acyl Ghrelin]
other names :
[acyl-protein thioesterase 1 isoform 6; Acyl-protein thioesterase 1; acyl-protein thioesterase 1; lysoPLA I; lysophospholipid-specific lysophospholipase; lysophospholipase I; Lysophospholipase 1; Lysophospholipase I]
products gene name :
[A-GHR]
other gene names :
[LYPLA1; LYPLA1; APT1; LPL1; APT-1; LPL-I; hAPT1; APT1; LPL1; APT-1; hAPT1; LPL-I; LysoPLA I]
uniprot entry name :
LYPA1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 62.5pg/ml-2000pg/ml. Sensitivity: 10pg/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of AG (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001266289.1
ncbi gb acc num :
NM_001279360.1
ncbi mol weight :
24,670 Da
ncbi pathways :
Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolism Pathway (477135); Metabolism Of Nitric Oxide Pathway (106222); ENOS Activation Pathway (106224); ENOS Activation And Regulation Pathway (106223)
ncbi summary :
This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013]
uniprot summary :
LYPLA1: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity. Belongs to the AB hydrolase 2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid Metabolism - glycerophospholipid; Phospholipase; EC 3.1.2.-. Chromosomal Location of Human Ortholog: 8q11.23. Cellular Component: mitochondrion; cytosol. Molecular Function: palmitoyl-(protein) hydrolase activity; lysophospholipase activity. Biological Process: negative regulation of Golgi to plasma membrane protein transport; regulation of nitric-oxide synthase activity; fatty acid metabolic process; nitric oxide metabolic process; protein depalmitoylation
size4 :
10x96-Strip-Wells