catalog number :
MBS018929
products type :
ELISA Kit
products full name :
Rat Wingless-Type Mmtv Integration Site Family, Member 9B ELISA Kit
products short name :
Wingless-Type Mmtv Integration Site Family, Member 9B
other names :
WNT9B; Protein Wnt-9b; protein Wnt-9b; protein Wnt-14b; wingless-type MMTV integration site family, member 15; wingless-type MMTV integration site family, member 9B; Protein Wnt-14b; Protein Wnt-15
products gene name :
WNT9B
other gene names :
WNT9B; WNT9B; WNT15; WNT14B; WNT14B; WNT15
uniprot entry name :
WNT9B_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
ELISA Type: Sandwich
ncbi acc num :
AAQ88584.1
ncbi mol weight :
39,001 Da
ncbi pathways :
Basal Cell Carcinoma Pathway 83113!!Basal Cell Carcinoma Pathway 525!!Class B/2 (Secretin Family Receptors) Pathway 106378!!GPCR Ligand Binding Pathway 161020!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Hedgehog Signaling Pathway 83063!!Hedgehog Signaling Pathway 474!!Hippo Signaling Pathway 749777!!Hippo Signaling Pathway 750388
ncbi summary :
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters . By similarity. Subunit structure: Component of the Wnt-Fzd-LRP5-LRP6 signaling complex that contains a WNT protein, a FZD protein and LRP5 or LRP6. Interacts directly in the complex with LRP6. Ref.5. Subcellular location: Secreted extracellular space extracellular matrix. Tissue specificity: Moderately expressed in fetal kidney and adult kidney. Also found in brain. Post-translational modification: Palmitoylation at Ser-216 is required for efficient binding to frizzled receptors. It is also required for subsequent palmitoylation at Cys-89. Palmitoylation is necessary for proper trafficking to cell surface . By similarity. Sequence similarities: Belongs to the Wnt family.