ELISA/assay

Canine Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 ELISA Kit

MBS018694

48-Strip-Wells

435 USD

ELISA Kit

Canine Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 ELISA Kit

Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1

NADPH oxidase 1 isoform 3; NADPH oxidase 1; NADPH oxidase 1; mitogenic oxidase 1; NADPH oxidase homolog-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); NADPH oxidase 1; Mitogenic oxidase 1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NOH-1

NOX1

NOX1; NOX1; MOX1; NOH1; NOH-1; GP91-2; MOX1; NOH1; NOX-1; MOX-1

NOX1_HUMAN

Canine

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NOX1 (hereafter termed this analyte) in undiluted original Canine serum, plasma and tissue homogenate samples.

425854820

NP_001258744.1

NM_001271815.1

Q9Y5S8

64,871 Da

HIF-1 Signaling Pathway (695200); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Osteoclast Differentiation Pathway (193147); Osteoclast Differentiation Pathway (193096); Phagosome Pathway (153910); Phagosome Pathway (153859); RAC1 Signaling Pathway (169355)

This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]

NOX1: NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Oxidoreductase; Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass; EC 1.-.-.-. Chromosomal Location of Human Ortholog: Xq22. Cellular Component: early endosome; integral to membrane; cell junction; NADPH oxidase complex. Molecular Function: protein binding; metal ion binding; superoxide-generating NADPH oxidase activity; Rac GTPase binding; NADP binding; voltage-gated proton channel activity. Biological Process: intracellular pH elevation; respiratory burst; cell migration; extracellular matrix organization and biogenesis; positive regulation of smooth muscle cell proliferation; superoxide metabolic process; positive regulation of JNK cascade; signal transduction; regulation of systemic arterial blood pressure by renin-angiotensin; NADP metabolic process; proton transport; regulation of blood pressure; positive regulation of cell proliferation; hydrogen peroxide metabolic process; angiogenesis; positive regulation of integrin biosynthetic process; inflammatory response; superoxide release

48-Strip-Wells

435 USD

96-Strip-Wells

600