Human Parathyroid Hormone Related Protein ELISA Kit | MyBioSource MBS017831 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Parathyroid Hormone Related Protein ELISA Kit

catalog :

MBS017831

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS017831

products type :

ELISA Kit

products full name :

Human Parathyroid Hormone Related Protein ELISA Kit

products short name :

[Parathyroid Hormone Related Protein]

other names :

[parathyroid hormone-related protein isoform 1 preproprotein; Parathyroid hormone-related protein; parathyroid hormone-related protein; PTH-rP; osteostatin; PTH-related protein; parathyroid hormone-like related protein; parathyroid hormone-like hormone; Parathyroid hormone-like protein; PLPCleaved into the following 3 chains:PTHrP[1-36]PTHrP[38-94]Osteostatin; Alternative name(s):; PTHrP[107-139]]

products gene name :

[PTHRP]

other gene names :

[PTHLH; PTHLH; HHM; PLP; BDE2; PTHR; PTHRP; PTHRP; PTH-rP; PTHrP; PLP]

uniprot entry name :

PTHR_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PTHRP (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

39995093

ncbi acc num :

NP_945317.1

ncbi gb acc num :

NM_198966.1

uniprot acc num :

P12272

ncbi mol weight :

20,194 Da

ncbi pathways :

Class B/2 (Secretin Family Receptors) Pathway (106378); Endochondral Ossification Pathway (198812); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356); Signaling Events Mediated By The Hedgehog Family Pathway (137950)

ncbi summary :

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq, Jul 2008]

uniprot summary :

PTHrP: a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Three alternatively spliced isoforms have been described. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 12p12.1-p11.2. Cellular Component: nucleoplasm; Golgi apparatus; extracellular space; cytoplasm; extracellular region. Molecular Function: peptide hormone receptor binding; hormone activity. Biological Process: epidermis development; negative regulation of transcription factor activity; negative regulation of chondrocyte differentiation; female pregnancy; G-protein signaling, adenylate cyclase activating pathway; osteoblast development; negative regulation of cell proliferation; cAMP metabolic process; epithelial cell differentiation; cell-cell signaling; regulation of gene expression; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; protein processing; alveolus development; skeletal development; surfactant homeostasis; endochondral ossification; endoderm development. Disease: Brachydactyly, Type E2

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage