Human Secreted Frizzled Related Protein 5 ELISA Kit | MyBioSource MBS017811 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Secreted Frizzled Related Protein 5 ELISA Kit

catalog :

MBS017811

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS017811

products type :

ELISA Kit

products full name :

Human Secreted Frizzled Related Protein 5 ELISA Kit

products short name :

Secreted Frizzled Related Protein 5

other names :

secreted frizzled-related protein 5; Secreted frizzled-related protein 5; secreted frizzled-related protein 5; FRP-1b; SARP-3; sFRP-5; frizzled-related protein 1b; secreted apoptosis related protein 3; secreted apoptosis-related protein 3; secreted frizzled-related protein 5; Frizzled-related protein 1b; FRP-1b; Secreted apoptosis-related protein 3

products gene name :

SFRP5

other gene names :

SFRP5; SFRP5; SARP3; FRP1B; SARP3; sFRP-5; FRP-1b; SARP-3

uniprot entry name :

SFRP5_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between Human SFRP5 and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

other info2 :

Intended Uses: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate SFRP5 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications. Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]

products description :

Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate SFRP5 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!

ncbi gi num :

188528609

ncbi acc num :

NP_003006.2

ncbi gb acc num :

NM_003015.3

uniprot acc num :

Q5T4F7

ncbi mol weight :

35,563 Da

ncbi pathways :

Wnt Signaling Pathway (83061); Wnt Signaling Pathway (471)

ncbi summary :

Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq, Jul 2008]

uniprot summary :

SFRP5: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. Belongs to the secreted frizzled-related protein (sFRP) family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 10q24.1. Cellular Component: extracellular space; integral to membrane. Molecular Function: G-protein coupled receptor activity; Wnt-protein binding; Wnt receptor activity. Biological Process: negative regulation of JNK activity; negative regulation of cell proliferation; convergent extension involved in axis elongation; anatomical structure morphogenesis; negative regulation of protein kinase B signaling cascade; visual perception; apoptosis; negative regulation of transcription factor activity; establishment and/or maintenance of cell polarity; digestive tract morphogenesis; cell differentiation; signal transduction

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage