Porcine Glypican 1 ELISA Kit | MyBioSource MBS017602 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Porcine Glypican 1 ELISA Kit

catalog :

MBS017602

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS017602

products type :

ELISA Kit

products full name :

Porcine Glypican 1 ELISA Kit

products short name :

[Glypican 1]

other names :

[glypican-1; Glypican-1; glypican-1; glypican proteoglycan 1; glypican 1]

products gene name :

[GPC1]

other gene names :

[GPC1; GPC1; glypican]

uniprot entry name :

GPC1_HUMAN

reactivity :

Porcine

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 3.12ng/ml-100ng/ml. Sensitivity: 1.0ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of GPAM (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

167001141

ncbi acc num :

NP_002072.2

ncbi gb acc num :

NM_002081.2

uniprot acc num :

P35052

ncbi mol weight :

61,680 Da

ncbi pathways :

A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Activation Of Rac Pathway (119530); Axon Guidance Pathway (105688); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Developmental Biology Pathway (477129); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Glycosaminoglycan Metabolism Pathway (645297); Glypican 1 Network Pathway (138010); Glypican Pathway (138083)

ncbi summary :

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]

uniprot summary :

GPC1: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. Associates (via the heparan sulfate side chains) with fibrillar APP-beta amyloid peptides in primitive and classic amyloid plaques and may be involved in the deposition of these senile plaques in the Alzheimer disease (AD) brain. Misprocessing of GPC1 is found in fibroblasts of patients with Niemann-Pick Type C1 disease. This is due to the defective deaminative degradation of heparan sulfate chains. Belongs to the glypican family. Protein type: Motility/polarity/chemotaxis; Extracellular matrix; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 2q35-q37. Cellular Component: proteinaceous extracellular matrix; extracellular space; lysosomal lumen; integral to plasma membrane; Golgi lumen; plasma membrane; endosome; lipid raft. Molecular Function: heparan sulfate proteoglycan binding; fibroblast growth factor binding; copper ion binding; laminin binding. Biological Process: chondroitin sulfate metabolic process; Schwann cell differentiation; phototransduction, visible light; axon guidance; myelin formation; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; heparan sulfate proteoglycan catabolic process; glycosaminoglycan metabolic process; negative regulation of fibroblast growth factor receptor signaling pathway; carbohydrate metabolic process; pathogenesis; retinoid metabolic process

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095