Human Mucin-7 ELISA Kit | MyBioSource MBS016943 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Mucin-7 ELISA Kit

catalog :

MBS016943

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS016943

products type :

ELISA Kit

products full name :

Human Mucin-7 ELISA Kit

products short name :

Mucin-7

other names :

mucin-7; Mucin-7; mucin-7; MUC-7; apo-MG2; salivary mucin-7; mucin 7, salivary; mucin 7, secreted; Apo-MG2; Salivary mucin-7

products gene name :

MUC7

other gene names :

MUC7; MUC7; MG2; MG2; MUC-7

uniprot entry name :

MUC7_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between Human MUC7 and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 5U/ml - 160U/ml. Sensitivity: 1.0U/ml.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated MUC7 concentrations in Human serum, plasma and other body fluids. Using Purified Human MUC7 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add MUC7 and MUC7 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of MUC7 in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated MUC7 concentrations in Human serum, plasma and other body fluids. Using Purified Human MUC7 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add MUC7 and MUC7 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of MUC7 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

222418649

ncbi acc num :

NP_001138479.1

ncbi gb acc num :

NM_001145007.1

uniprot acc num :

Q8TAX7

ncbi mol weight :

39,159 Da

ncbi pathways :

Metabolism Of Proteins Pathway (106230); O-linked Glycosylation Of Mucins Pathway (530747); Post-translational Protein Modification Pathway (161012); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352); Termination Of O-glycan Biosynthesis Pathway (530748)

ncbi summary :

This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.[provided by RefSeq, Feb 2009]

uniprot summary :

MUC7: May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili. Genetic variations in MUC7 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: Golgi lumen. Molecular Function: protein binding. Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification. Disease: Asthma, Susceptibility To

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage