Monkey Glucoprotein 130 ELISA Kit | MyBioSource MBS015958 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Monkey Glucoprotein 130 ELISA Kit

catalog :

MBS015958

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS015958

products type :

ELISA Kit

products full name :

Monkey Glucoprotein 130 ELISA Kit

products short name :

[Glucoprotein 130]

other names :

[gp130; Interleukin-6 receptor subunit beta; interleukin-6 receptor subunit beta; CD130 antigen; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; membrane glycoprotein gp130; interleukin receptor beta chain; oncostatin-M receptor subunit alpha; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; interleukin 6 signal transducer (gp130, oncostatin M receptor); CDw130; Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; Oncostatin-M receptor subunit alpha]

products gene name :

[GP130]

other gene names :

[IL6ST; IL6ST; CD130; GP130; CDW130; IL-6RB; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6R-beta; IL-6RB; gp130]

uniprot entry name :

IL6RB_HUMAN

reactivity :

Monkey

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Sandwich (Quantitative). Detection Range: 31.2 ng/ml - 1000 ng/ml. Sensitivity: 5.0 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GP130 (hereafter termed "analyte") in undiluted original Monkey body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

1246098

ncbi acc num :

AAB35921.1

uniprot acc num :

P40189

ncbi mol weight :

103,537 Da

ncbi pathways :

Adipogenesis Pathway (198832); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL-6 Signaling Pathway (198864); IL27-mediated Signaling Events Pathway (137929); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Interleukin-11 Signaling Pathway (698753); Interleukin-6 Signaling Pathway (205111)

ncbi summary :

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2010]

uniprot summary :

gp130: gp130 is a ubiquitously expressed type I cytokine family receptor. The receptor systems for IL6, LIF, OSM, CNTF, IL11 AND CT1 utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not directly bind IL6. May have a role in embryonic development. Contains 5 fibronectin type III domains and 1 immunoglobulin-like C2-type domain. Two alternatively spliced isoforms have been described. Protein type: Receptor, cytokine; Membrane protein, integral. Chromosomal Location of Human Ortholog: 5q11.2. Cellular Component: extracellular space; membrane; cell soma; oncostatin-M receptor complex; dendrite; extracellular region; plasma membrane; interleukin-6 receptor complex; external side of plasma membrane. Molecular Function: interleukin-11 binding; interleukin-27 receptor activity; protein homodimerization activity; oncostatin-M receptor activity; leukemia inhibitory factor receptor activity; interleukin-6 receptor activity; interleukin-11 receptor activity; protein binding; interleukin-6 binding; interleukin-6 receptor binding; growth factor binding; ciliary neurotrophic factor receptor activity; ciliary neurotrophic factor receptor binding. Biological Process: glycogen metabolic process; viral reproduction; leukemia inhibitory factor signaling pathway; cytokine and chemokine mediated signaling pathway; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of osteoblast differentiation; positive regulation of tyrosine phosphorylation of Stat1 protein; regulation of Notch signaling pathway; positive regulation of acute inflammatory response; response to cytokine stimulus; positive regulation of cell proliferation; positive regulation of T cell proliferation; positive regulation of adaptive immune response; negative regulation of apoptosis; positive regulation of astrocyte differentiation

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095