This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Tyrosinase ELISA Kit
catalog :
MBS015936
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS015936
products type :
ELISA Kit
products full name :
Mouse Tyrosinase ELISA Kit
products short name :
[Tyrosinase]
other names :
[tyrosinase; Tyrosinase; tyrosinase; LB24-AB; SK29-AB; monophenol monooxygenase; oculocutaneous albinism IA; tumor rejection antigen AB; tyrosinase; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB]
products gene name :
[TYR]
other gene names :
[TYR; TYR; CMM8; OCA1A; OCAIA; SHEP3]
uniprot entry name :
TYRO_HUMAN
reactivity :
Mouse
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TYR (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
4507753
ncbi acc num :
NP_000363.1
ncbi gb acc num :
NM_000372.4
uniprot acc num :
P14679
ncbi mol weight :
60,393 Da
ncbi pathways :
(S)-reticuline Biosynthesis II Pathway (547499); (S)-reticuline Biosynthesis II Pathway (138845); Catecholamine Biosynthesis, Tyrosine = Dopamine = Noradrenaline = Adrenaline Pathway (413357); Catecholamine Biosynthesis, Tyrosine = Dopamine = Noradrenaline = Adrenaline Pathway (468235); L-dopachrome Biosynthesis Pathway (545322); L-dopachrome Biosynthesis Pathway (545496); Melanogenesis Pathway (83092); Melanogenesis Pathway (504); Riboflavin Metabolism Pathway (83012); Riboflavin Metabolism Pathway (398)
ncbi summary :
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
uniprot summary :
TYR: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. Increased expression after UVB irradiation. Belongs to the tyrosinase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cofactor and Vitamin Metabolism - riboflavin; Membrane protein, integral; Amino Acid Metabolism - tyrosine; EC 1.14.18.1; Oxidoreductase. Chromosomal Location of Human Ortholog: 11q14.3. Cellular Component: perinuclear region of cytoplasm; lysosome; cytoplasm; melanosome membrane; integral to membrane; melanosome; Golgi-associated vesicle. Molecular Function: protein binding; protein homodimerization activity; copper ion binding; protein heterodimerization activity; monophenol monooxygenase activity. Biological Process: cell proliferation; visual perception; thymus development; melanin biosynthetic process from tyrosine; eye pigment biosynthetic process. Disease: Albinism, Ocular, With Sensorineural Deafness; Albinism, Oculocutaneous, Type Ib; Albinism, Oculocutaneous, Type Ia; Skin/hair/eye Pigmentation, Variation In, 3
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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