ELISA/assay

Human Matrilysin ELISA Kit

MBS015774

48-Strip-Wells

435 USD

ELISA Kit

Human Matrilysin ELISA Kit

Matrilysin

matrilysin preproprotein; Matrilysin; matrilysin; matrin; pump-1 protease; uterine matrilysin; uterine metalloproteinase; matrix metalloproteinase-7; matrix metalloproteinase 7 (matrilysin, uterine); matrix metallopeptidase 7 (matrilysin, uterine); Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinase

MAT

MMP7; MMP7; MMP-7; MPSL1; PUMP-1; MPSL1; PUMP1; MMP-7

MMP7_HUMAN

Human

Store all reagents at 2-8 degree C

Assay Type: Sandwich

4505219

NP_002414.1

NM_002423.3

P09237

29,677 Da

AGE/RAGE Pathway (698754); Activation Of Matrix Metalloproteinases Pathway (576264); Alpha6-Beta4 Integrin Signaling Pathway (198807); Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Collagen Formation Pathway (645288); Degradation Of Collagen Pathway (730309); Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Matrix Metalloproteinases Pathway (198900); Syndecan-1-mediated Signaling Events Pathway (138046)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

MMP7: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. Belongs to the peptidase M10A family. Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.24.23. Chromosomal Location of Human Ortholog: 11q22.2. Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region. Molecular Function: zinc ion binding; metalloendopeptidase activity. Biological Process: response to drug; extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; defense response to Gram-positive bacterium; antibacterial peptide biosynthetic process; defense response to Gram-negative bacterium; proteolysis; antibacterial peptide secretion; regulation of cell proliferation

48-Strip-Wells

435 USD

96-Strip-Wells

600