catalog number :
MBS015681
products type :
ELISA Kit
products full name :
Porcine Ornithine Decarboxylase ELISA Kit
products short name :
Ornithine Decarboxylase
other names :
ornithine decarboxylase; Ornithine decarboxylase; ornithine decarboxylase; ornithine decarboxylase 1
other gene names :
ODC1; ODC1; ODC; ODC
uniprot entry name :
DCOR_HUMAN
specificity :
No significant cross-reactivity or interference between Porcine ODC and analogues was observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intended Uses: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate ODC concentrations in Porcine serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications. Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]
products description :
Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate ODC concentrations in Porcine serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!
ncbi acc num :
NP_002530.1
ncbi gb acc num :
NM_002539.1
ncbi mol weight :
51,148 Da
ncbi pathways :
Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Glutathione Metabolism Pathway (82973); Glutathione Metabolism Pathway (343); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Metabolism Of Polyamines Pathway (106193); Polyamine Biosynthesis, Arginine = Ornithine = Putrescine Pathway (413403); Polyamine Biosynthesis, Arginine = Ornithine = Putrescine Pathway (468321); Regulation Of Ornithine Decarboxylase (ODC) Pathway (106176)
ncbi summary :
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]
uniprot summary :
ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]. Protein type: EC 4.1.1.17; Amino Acid Metabolism - arginine and proline; Lyase; Other Amino Acids Metabolism - glutathione; Cell cycle regulation. Chromosomal Location of Human Ortholog: 2p25. Cellular Component: cytoplasm; cytosol. Molecular Function: protein homodimerization activity; ornithine decarboxylase activity. Biological Process: response to virus; positive regulation of cell proliferation; regulation of protein catabolic process; regulation of amino acid metabolic process; kidney development; putrescine biosynthetic process from ornithine; polyamine metabolic process. Disease: Colorectal Cancer