catalog number :
MBS015581
products type :
ELISA Kit
products full name :
Porcine Follistatin ELISA Kit
products short name :
[Follistatin]
other names :
[follistatin; Follistatin; follistatin; activin-binding protein; follistatin isoform FST317; follistatin; Activin-binding protein]
products gene name :
[FS]
other gene names :
[FST; FST; FS; FS]
uniprot entry name :
FST_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FS (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
AAA35851.1
ncbi mol weight :
38,007 Da
ncbi pathways :
Antagonism Of Activin By Follistatin Pathway (730350); BMP Receptor Signaling Pathway (137948); Integrated Pancreatic Cancer Pathway (711360); Signal Transduction Pathway (477114); Signaling By Activin Pathway (730349); TGF Beta Signaling Pathway (198810); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)
ncbi summary :
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]
uniprot summary :
FST: Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 5q11.2. Cellular Component: cytoplasm; extracellular region; nucleus. Molecular Function: heparan sulfate proteoglycan binding; signal transducer activity; protein binding; activin binding. Biological Process: BMP signaling pathway; positive regulation of hair follicle development; negative regulation of activin receptor signaling pathway; negative regulation of cell differentiation; hair follicle morphogenesis; gamete generation; hemopoietic progenitor cell differentiation; keratinocyte proliferation; negative regulation of transcription from RNA polymerase II promoter; pattern specification process; skeletal development; female gonad development; odontogenesis of dentine-containing teeth. Disease: Polycystic Ovary Syndrome 1
size4 :
10x96-Strip-Wells