This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Bovine Glycoprotein VI, Platelet ELISA Kit
catalog :
MBS015442
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS015442
products type :
ELISA Kit
products full name :
Bovine Glycoprotein VI, Platelet ELISA Kit
products short name :
[Glycoprotein VI, Platelet]
other names :
[glycoprotein VI, partial; Platelet glycoprotein VI; platelet glycoprotein VI; glycoprotein 6; platelet collagen receptor; glycoprotein VI (platelet); Glycoprotein 6]
products gene name :
[GP6]
other gene names :
[GP6; GP6; GPIV; GPVI; BDPLT11; GPVI]
uniprot entry name :
GPVI_HUMAN
reactivity :
Bovine
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 6.25 ng/ml - 200 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GP6 (hereafter termed this analyte) in undiluted original Bovine serum, plasma and tissue homogenate samples.
ncbi gi num :
26985217
ncbi acc num :
AAN86273.1
uniprot acc num :
Q9HCN6
ncbi mol weight :
36,866 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (106062); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); GPVI-mediated Activation Cascade Pathway (106036); Hemostasis Pathway (106028); Platelet Adhesion To Exposed Collagen Pathway (106030); Platelet Activation, Signaling And Aggregation Pathway (106034)
ncbi summary :
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
uniprot summary :
GPVI: Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2. Defects in GP6 are the cause of bleeding disorder platelet-type 11 (BDPLT11). BDPLT11 is a mild to moderate bleeding disorder caused by defective platelet activation and aggregation in response to collagen. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.4. Cellular Component: cell surface; integral to plasma membrane; plasma membrane. Molecular Function: collagen binding; protein binding; transmembrane receptor activity; receptor activity. Biological Process: platelet activation; blood coagulation; enzyme linked receptor protein signaling pathway; leukocyte migration. Disease: Bleeding Disorder, Platelet-type, 11
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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