catalog number :
MBS015372
products type :
ELISA Kit
products full name :
Rat Alpha B-Crystallin ELISA Kit
products short name :
Alpha B-Crystallin
other names :
CRYAB; Alpha-crystallin B chain; crystallin, alpha B; Alpha(B)-crystallin; Alpha-crystallin B chain; Alpha(B)-crystallin
products gene name :
CRYAB
other gene names :
CRYAB; CRYAB
uniprot entry name :
CRYAB_PIG
specificity :
No significant cross-reactivity or interference between Rat CRYAB and analogues was observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intended Uses: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate CRYAB concentrations in Rat serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications. Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]
products description :
Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate CRYAB concentrations in Rat serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!
ncbi acc num :
ACA97071.1
ncbi mol weight :
20,129 Da
ncbi pathways :
Protein Processing In Endoplasmic Reticulum Pathway (167312); Protein Processing In Endoplasmic Reticulum Pathway (167190)
uniprot summary :
CRYAB: a major structural protein of the eye lens. A member of the small heat shock protein (sHSP also known as the HSP20) family. Alpha-B is expressed in the lens as well as other tissues. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Protein type: Chaperone; Heat shock protein. Cellular Component: mitochondrion; cytoplasm; plasma membrane; cytosol; Z disc; nucleus. Molecular Function: protein homodimerization activity; metal ion binding; unfolded protein binding; structural constituent of eye lens. Biological Process: tubulin folding; lens development in camera-type eye; muscle development; negative regulation of intracellular transport; response to hydrogen peroxide; response to hypoxia; negative regulation of caspase activity; protein homooligomerization