catalog number :
MBS015194
products type :
ELISA Kit
products full name :
Human Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG ELISA Kit
products short name :
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG
other names :
myeloblastin; Myeloblastin; myeloblastin; C-ANCA antigen; wegener autoantigen; leukocyte proteinase 3; neutrophil proteinase 4; azurophil granule protein 7; serine proteinase, neutrophil; Wegener granulomatosis autoantigen; proteinase 3; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen
products gene name :
MPO-ANCA IgG
other gene names :
PRTN3; PRTN3; MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA; MBN; PR-3; PR3; NP-4
uniprot entry name :
PRTN3_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
ELISA Type: Sandwich
ncbi acc num :
NP_002768.3
ncbi gb acc num :
NM_002777.3
ncbi mol weight :
27,807 Da
ncbi pathways :
C-MYB Transcription Factor Network Pathway 138073
uniprot summary :
Function: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Catalytic activity: Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala- -Xaa- > -Val- -Xaa-. Ref.18. Sequence similarities: Belongs to the peptidase S1 family. Elastase subfamily.Contains 1 peptidase S1 domain. Sequence caution: The sequence AAA36342.1 differs from that shown. Reason: Frameshift at positions 34 and 39. The sequence CAA39598.1 differs from that shown. Reason: Erroneous initiation.