ELISA/assay

Human Alkaline Phosphatase, Liver/Bone/Kidney ELISA Kit

MBS015132

48-Strip-Wells

435 USD

ELISA Kit

Human Alkaline Phosphatase, Liver/Bone/Kidney ELISA Kit

Alkaline Phosphatase, Liver/Bone/Kidney

alkaline phosphatase, placental type preproprotein; Alkaline phosphatase, placental type; alkaline phosphatase, placental type; Regan isozyme; glycerophosphatase; alkaline phosphomonoesterase; placental alkaline phosphatase 1; alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1

ALPL

ALPP; ALPP; ALP; PALP; PLAP; PLAP-1; PLAP; PLAP-1

PPB1_HUMAN

Human

535

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 15.6U/L-500U/L. Sensitivity: 2.0U/L.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ALPL (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.

94721246

NP_001623.3

NM_001632.3

P05187

57,954 Da

Folate Biosynthesis Pathway (83018); Folate Biosynthesis Pathway (404)

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. [provided by RefSeq, Jul 2008]

ALPP: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3 untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. [provided by RefSeq, Jul 2008]. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cofactor and Vitamin Metabolism - folate biosynthesis; Phosphatase (non-protein); EC 3.1.3.1; Cell surface; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 2q37. Cellular Component: cell surface; integral to membrane; plasma membrane. Molecular Function: zinc ion binding; alkaline phosphatase activity; magnesium ion binding. Biological Process: dephosphorylation

48-Strip-Wells

435 USD

96-Strip-Wells

600