Monkey Follistatin ELISA Kit | MyBioSource MBS014774 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Monkey Follistatin ELISA Kit

catalog :

MBS014774

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS014774

products type :

ELISA Kit

products full name :

Monkey Follistatin ELISA Kit

products short name :

Follistatin

other names :

follistatin; Follistatin; follistatin; activin-binding protein; follistatin isoform FST317; follistatin; Activin-binding protein

products gene name :

other gene names :

FST; FST; FS; FS

uniprot entry name :

FST_HUMAN

reactivity :

Monkey

specificity :

No significant cross-reactivity or interference between Monkey FS and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intended Uses: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate FS concentrations in Monkey serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]

products description :

Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate FS concentrations in Monkey serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!

ncbi gi num :

182721

ncbi acc num :

AAA35851.1

uniprot acc num :

P19883

ncbi mol weight :

38,007 Da

ncbi pathways :

Antagonism Of Activin By Follistatin Pathway (730350); BMP Receptor Signaling Pathway (137948); Integrated Pancreatic Cancer Pathway (711360); Signal Transduction Pathway (477114); Signaling By Activin Pathway (730349); TGF Beta Signaling Pathway (198810); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)

ncbi summary :

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]

uniprot summary :

FST: Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5q11.2. Cellular Component: cytoplasm; extracellular region; nucleus. Molecular Function: heparan sulfate proteoglycan binding; protein binding; signal transducer activity; activin binding. Biological Process: positive regulation of hair follicle development; BMP signaling pathway; negative regulation of activin receptor signaling pathway; negative regulation of cell differentiation; hair follicle morphogenesis; gamete generation; hemopoietic progenitor cell differentiation; negative regulation of transcription from RNA polymerase II promoter; keratinocyte proliferation; pattern specification process; skeletal development; female gonad development; odontogenesis of dentine-containing teeth. Disease: Polycystic Ovary Syndrome 1

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage