catalog number :
MBS014500
products type :
ELISA Kit
products full name :
Porcine Pepsin ELISA Kit
products short name :
Pepsin
other names :
pepsin A-5 preproprotein; Pepsin A-5; pepsin A-5; pepsinogen-5; pepsinogen A5; pepsinogen 5, group I (pepsinogen A); Pepsinogen-5
other gene names :
PGA5; PGA5
uniprot entry name :
PEPA5_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PP (hereafter termed this analyte) in undiluted original Porcine serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_055039.1
ncbi gb acc num :
NM_014224.3
ncbi mol weight :
41,993 Da
ncbi pathways :
Protein Digestion And Absorption Pathway (172847); Protein Digestion And Absorption Pathway (171868)
ncbi summary :
This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015]
uniprot summary :
PGA5: Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. Belongs to the peptidase A1 family. Protein type: EC 3.4.23.1; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 11q13. Molecular Function: aspartic-type endopeptidase activity. Biological Process: digestion; proteolysis