product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Follistatin ELISA Kit
catalog :
MBS014428
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS014428
products type :
ELISA Kit
products full name :
Human Follistatin ELISA Kit
products short name :
Follistatin
other names :
follistatin; Follistatin; follistatin; activin-binding protein; follistatin isoform FST317; follistatin; Activin-binding protein
products gene name :
FS
other gene names :
FST; FST; FS; FS
uniprot entry name :
FST_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich
ncbi gi num :
182721
ncbi acc num :
AAA35851.1
uniprot acc num :
P19883
ncbi mol weight :
38,007 Da
ncbi pathways :
Antagonism Of Activin By Follistatin Pathway (730350); BMP Receptor Signaling Pathway (137948); Integrated Pancreatic Cancer Pathway (711360); Signal Transduction Pathway (477114); Signaling By Activin Pathway (730349); TGF Beta Signaling Pathway (198810); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)
ncbi summary :
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]
uniprot summary :
FST: Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5q11.2. Cellular Component: cytoplasm; extracellular region; nucleus. Molecular Function: heparan sulfate proteoglycan binding; signal transducer activity; protein binding; activin binding. Biological Process: BMP signaling pathway; positive regulation of hair follicle development; negative regulation of activin receptor signaling pathway; negative regulation of cell differentiation; hair follicle morphogenesis; gamete generation; hemopoietic progenitor cell differentiation; negative regulation of transcription from RNA polymerase II promoter; keratinocyte proliferation; pattern specification process; skeletal development; female gonad development; odontogenesis of dentine-containing teeth. Disease: Polycystic Ovary Syndrome 1
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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