catalog number :
MBS014259
products type :
ELISA Kit
products full name :
Human Chondroitin Sulfate ELISA Kit
products short name :
Chondroitin Sulfate
other names :
chondroitin sulfate N-acetylgalactosaminyltransferase 1; Chondroitin sulfate N-acetylgalactosaminyltransferase 1; chondroitin sulfate N-acetylgalactosaminyltransferase 1; beta4GalNAcT-1; chondroitin beta1,4 N-acetylgalactosaminyltransferase; chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1; chondroitin sulfate N-acetylgalactosaminyltransferase 1; Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1
other gene names :
CSGALNACT1; CSGALNACT1; ChGn; CSGalNAcT-1; beta4GalNAcT; CHGN; GALNACT1; CsGalNAcT-1
uniprot entry name :
CGAT1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 6.25 mug/ml - 200 mug/ml. Sensitivity: 1.0 mug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CS (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_060841.5
ncbi gb acc num :
NM_018371.4
ncbi mol weight :
61,294 Da
ncbi pathways :
Chondroitin Sulfate Biosynthesis Pathway (645309); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Disease Pathway (530764); Glycogen Storage Diseases Pathway (980468); Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway (82982); Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway (356); Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway (413364); Glycosaminoglycan Biosynthesis, Chondroitin Sulfate Backbone Pathway (468251); Glycosaminoglycan Metabolism Pathway (645297); MPS I - Hurler Syndrome Pathway (685537)
uniprot summary :
ChGn: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.4.1.174; Glycan Metabolism - chondroitin sulfate biosynthesis; Membrane protein, integral; Transferase. Chromosomal Location of Human Ortholog: 8p21.3. Cellular Component: Golgi membrane; integral to Golgi membrane; intracellular. Molecular Function: glucuronosyltransferase activity; metal ion binding; acetylgalactosaminyltransferase activity; peptidoglycan glycosyltransferase activity; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Biological Process: nervous system development; anatomical structure morphogenesis; extracellular matrix organization and biogenesis; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; chondroitin sulfate proteoglycan biosynthetic process; pathogenesis; cell recognition; UDP-N-acetylgalactosamine metabolic process; chondroitin sulfate metabolic process; cell proliferation; UDP-glucuronate metabolic process; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparin biosynthetic process; cartilage development; proteoglycan biosynthetic process; carbohydrate metabolic process; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process; endochondral ossification