This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Hamster Cytochrome P450 7A1 ELISA Kit
catalog :
MBS013994
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS013994
products type :
ELISA Kit
products full name :
Hamster Cytochrome P450 7A1 ELISA Kit
products short name :
[Cytochrome P450 7A1]
other names :
[cholesterol 7-alpha-monooxygenase; Cholesterol 7-alpha-monooxygenase; cholesterol 7-alpha-monooxygenase; cytochrome P450 7A1; cholesterol 7-alpha-hydroxylase; cytochrome P450, subfamily VIIA polypeptide 1; cytochrome P450, family 7, subfamily A, polypeptide 1; CYPVII; Cholesterol 7-alpha-hydroxylase; Cytochrome P450 7A1]
products gene name :
[CYP7A1]
other gene names :
[CYP7A1; CYP7A1; CP7A; CYP7; CYPVII; CYP7]
uniprot entry name :
CP7A1_HUMAN
reactivity :
Hamster
sequence length :
504
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CYP7A1 (hereafter termed "analyte") in undiluted original Hamster body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
166295200
ncbi acc num :
NP_000771.2
ncbi gb acc num :
NM_000780.3
uniprot acc num :
P22680
ncbi mol weight :
57,661 Da
ncbi pathways :
Bile Acid And Bile Salt Metabolism Pathway (106144); Bile Acid Biosynthesis, Cholesterol = Cholate/chenodeoxycholate Pathway (413432); Bile Acid Biosynthesis, Cholesterol = Cholate/chenodeoxycholate Pathway (468297); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Biological Oxidations Pathway (105698); Cytochrome P450 - Arranged By Substrate Type Pathway (105700); Drug Induction Of Bile Acid Pathway (698755); Endogenous Sterols Pathway (105701); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977)
ncbi summary :
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010]
uniprot summary :
CYP7A1: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis. Belongs to the cytochrome P450 family. Protein type: EC 1.14.13.17; Oxidoreductase; Lipid Metabolism - primary bile acid biosynthesis; Endoplasmic reticulum. Chromosomal Location of Human Ortholog: 8q11-q12. Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle. Molecular Function: cholesterol 7-alpha-monooxygenase activity; iron ion binding; heme binding. Biological Process: bile acid biosynthetic process; cholesterol homeostasis; bile acid metabolic process; xenobiotic metabolic process; cellular lipid metabolic process; cholesterol catabolic process; sterol metabolic process; transmembrane transport
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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